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Fragment 176-191

low risk

Also: HGH Fragment 176-191 · HGH Frag · Fat loss peptide

Preliminary Research Only

Fragment 176-191 is a C-terminal HGH fragment associated with fat metabolism. Related to AOD-9604. Animal studies show selective lipolytic effects. Human clinical data is very limited — primarily animal and anecdotal. Heavily marketed but evidence is thin.

Molecular Weight
1817.1 Da
Formula
C78H125N23O23S2
Common Dosing
250–500 mcg/day SC, morning on empty stomach
Category
research
Last Reviewed
2025-01-15

Reported Benefits

Lipolysis / fat reduction

Preliminary 8 studies

Animal models show selective fat reduction. Human data essentially anecdotal.

Mechanism of Action

Selectively activates lipolysis without affecting IGF-1 or insulin sensitivity via C-terminal HGH mechanism.

AOD-9604 vs. Fragment 176-191

Closely related compounds — AOD-9604 is the modified/stabilized version. AOD-9604 at least has Phase III trial data (even though it failed). Fragment 176-191 human data is essentially absent beyond Phase I safety.

Evidence claims circulating online significantly exceed what the actual research supports.

Regulatory Status

Research Only

Safety Profile

Side Effects

  • Mild injection site reactions
  • Possible mild hypoglycemia

Contraindications

  • Pregnancy

Primary Uses

Fat lossLipolysis

Related Peptides

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Disclaimer: This information is for educational and research purposes only. Not medical advice. Consult a qualified healthcare provider before using any compound.