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About Ercle

What Ercle Is

Ercle is an independent peptide research database and intelligence publication. We profile peptides with honest evidence ratings, regulatory status, and clinical context — for practitioners, researchers, and informed patients.

What Ercle Is Not

  • We are not a medical practice. We don't give medical advice.
  • We are not affiliated with any peptide vendor, compounding pharmacy, or supplement company.
  • We are not a regulatory authority. We interpret regulations but do not make them.

Our Independence Policy

No vendor relationships. We accept no compensation, product samples, sponsored content, or advertising from peptide vendors, compounding pharmacies, research chemical suppliers, or supplement companies.

Advertising policy: Ercle accepts advertising from professional service providers (labs, software, education), non-peptide healthcare companies, and non-competing publications. No editorial influence. See the Advertise page for details.

No affiliate relationships for any compound or supplier.

How We Rate Evidence

We use a four-tier rating system:

Strong

Multiple Phase III RCTs; FDA approval or equivalent; consistent independent replication.

Moderate

Phase II RCTs; multiple Phase I/II human studies; independent replication; mechanistic data supported by human PKs.

Preliminary

Animal models with consistent results; limited human data; single research group; mechanistically plausible.

Insufficient

Single animal study or in vitro only; contradictory findings; theoretical mechanism.

We do not adjust ratings for anecdotal reports, community testimonials, or marketing claims.

How We Update

Evidence ratings are reviewed annually at minimum. When significant new studies publish, we update on a rolling basis. The "Last Reviewed" date on each entry reflects when we last assessed the evidence.

Medical Review Board

We are actively building our clinical review board of physicians, pharmacists, and researchers. Interested in contributing?

editor@ercle.com

Regulatory Disclaimer

Regulatory landscapes change. Our Regulatory Tracker reflects our best understanding of current FDA status and should not be used as legal advice. Always verify with FDA.gov and qualified counsel.

Corrections Log

We correct mistakes promptly and transparently. All corrections are logged here.

Date Article Correction Status
No corrections on record.

Contact

For corrections, research submissions, or press inquiries: editor@ercle.com